Brown Tumour of Hyperparathyroidism, a benign latency in the jaws: A Review of Literature. Literature.

Background: To inculcate awareness about the importance of thorough screening of the patients presenting with giant cell lesions in the jaw bones for clinical, biochemical and radiological features of hyperparathyroidism. Material and Methods: The history, physical examination, laboratory values, imaging and pathologic findings are described in a 32-year-old woman, presenting with brown tumour lesion in mandible, due to primary hyperparathyroidism. A systematic review of published literature from PubMed is added, which highlights the importance of a thorough diagnostic workup and selection of appropriate treatment modality. Results: In the case presented, after Parathyroid adenoma excision, within thirty minutes, the serum values of Parathormone and Calcium returned to normalcy and spontaneous regression of the brown tumour was noted. Also, the review of literature emphasized the need for systemic investigations of suspected giant cell jaw lesions and established that parathyroidectomy can be considered the primary treatment modality for brown tumours of the jaw due to hyperparathyroidism. Conclusion: Radiolucent lesions of the jaws showing giant cells on histopathology should raise suspicion of hyperparathyroidism. This case emphasizes the importance of a detailed systemic investigation for all lesions in the maxillofacial region.

Reactive Lesions Of Oral Cavity.

Oral mucosa is subjected constantly to external and internal stimuli that can give rise to reactive lesions. These lesions are non- neoplastic in nature. They manifest a spectrum of diseases that range from developmental, inflammatory, and reactive to neoplastic changes. Reactive lesions are typically gives response to chronic inflammation caused by various forms of low grade chronic irritations to the oral mucosa such as dental plaque and calculus, sharp edges of grossly carious teeth, faulty dental restorations, chronic biting habits, ill-fitting dental/oral appliances and food impactions. These lesions have a very similar appearance to benign neoplastic proliferations. This similarity is troublesome in differential diagnosis among them. Different types of localized reactive lesions of oral cavity are focal fibrous hyperplasia (FFH), pyogenic granuloma (PG), irritational fibroma, peripheral giant cell granuloma (PGCG), peripheral ossifying fibroma (POF), fibro-epithelial hyperplasia/polyp, inflammatory fibrous hyperplasia, and inflammatory gingival hyperplasia.